Found a good article on selecting fuses for your project on a website called “Power Electronics”
Here is a snippet from that article, listing the design factors explained in the article.
Proper selection of an input fuse for a dc-dc converter involves understanding and consideration of the following factors: 1. Voltage Rating 2. Current Rating 3. Interrupting Rating 4. Temperature Derating 5. Melting Integral (I2t) 6. Maximum Circuit Fault Current 7. Required Agency Approvals 8. Mechanical Considerations